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Should we treat pyrexia? And how do we do it? - Critical Care
WEBOct 3, 2016 — The concept of pyrexia as a protective physiological response to aid in host defence has been challenged with the awareness of the severe metabolic stress induced by pyrexia. The host response to pyrexia varies, however, according to the disease profile and severity and, as such, the management of pyrexia should differ; for example, …
Ccforum.biomedcentral.comPyrexia: aetiology in the ICU | Critical Care | Full Text - BioMed …
WEBSep 1, 2016 — Most episodes of pyrexia are due to infections, but incidence estimates of infectious and noninfectious aetiologies are limited by studies with small sample size and inconsistent reporting of noninfectious aetiologies. pyrexia commonly triggers a full septic work-up, but on its own is a poor predictor of culture-positivity.
Ccforum.biomedcentral.comThe pathophysiological basis and consequences of fever
WEBJul 14, 2016 — The normal human temperature is considered to be 37 °C, but may vary by up to 1 °C in healthy individuals [1]. Elevated core temperature is a common finding in intensive care, affecting up to 70 % of patients [2]. Despite the general usage of the terms ‘pyrexia’, ‘fever’, and ‘hyperthermia’, they are not yet universally defined.
Ccforum.biomedcentral.comPyrexia: aetiology in the ICU - BioMed Central
WEBnoninfectious pyrexia, is more commonly observed in patients with hyperthermia. Most episodes of pyrexia are due to infections, but incidence estimates of infectious and noninfectious aetiologies are limited by studies with small sample size and inconsistent reporting of noninfectious aetiologies. pyrexia commonly triggers a full septic work-up,
Ccforum.biomedcentral.comThe pathophysiological basis and consequences of fever
WEBApr 12, 2015 — meaning simply ‘heat’, and pyrexia comes from the Greek ‘pyr’, meaning fire or fever. Some sources use the terms interchangeably, whereas others preserve ‘fever’ to mean a raised temperature caused by the action of thermoregula-tory pyrogens on the hypothalamus; for instance, in sepsis and inflammatory conditions [3].
Ccforum.biomedcentral.comFever and hypothermia represent two populations of sepsis …
WEBOct 21, 2021 — Background Fever and hypothermia have been observed in septic patients. Their influence on prognosis is subject to ongoing debates. Methods We did a secondary analysis of a large clinical dataset from a quality improvement trial. A binary logistic regression model was calculated to assess the association of the thermal response with …
Ccforum.biomedcentral.comTargeted temperature control following traumatic brain injury: …
WEBMay 20, 2024 — Aims and scope The aim of this panel was to develop consensus recommendations on targeted temperature control (TTC) in patients with severe traumatic brain injury (TBI) and in patients with moderate TBI who deteriorate and require admission to the intensive care unit for intracranial pressure (ICP) management. Methods A group …
Ccforum.biomedcentral.comShould we treat pyrexia? And how do we do it?
WEBThe cost of pyrexia should be considered in several ways. pyrexia has a metabolic cost such that cooling fe-brile ICU patients will reduce oxygen consumption by 10 % per °C [6]. Small studies in sedated patients dem-onstrated a significant reduction in VO 2 (the rate of oxy-gen consumption) and VCO 2 (the rate of carbon dioxide
Ccforum.biomedcentral.comThe neurological and cognitive consequences of hyperthermia
WEBJul 14, 2016 — An elevated temperature has many aetiologies, both infective and non-infective, and while the fever of sepsis probably confers benefit, there is increasing evidence that the central nervous system is particularly vulnerable to damage from hyperthermia. A single episode of hyperthermia may cause short-term neurological and cognitive …
Ccforum.biomedcentral.comTemperature control after cardiac arrest - Critical Care
WEBNov 24, 2022 — Most of the patients who die after cardiac arrest do so because of hypoxic-ischemic brain injury (HIBI). Experimental evidence shows that temperature control targeted at hypothermia mitigates HIBI. In 2002, one randomized trial and one quasi-randomized trial showed that temperature control targeted at 32–34 °C improved neurological outcome …
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