Myelination
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Myelin sheath: Myelination, function, clinical relations - Kenhub
WEBOct 26, 2023 · Myelin is made up of lipids and proteins, a fatty substance with a whitish appearance. It is made up of many concentric layers of plasma membrane to make up the myelin sheath around axons. Myelin sheath and myelin function are therefore the same, to increase the speed of nerve impulses.
Kenhub.comMyelination - an overview | ScienceDirect Topics
WEBMyelin is a lipid-protein membrane that is spirally wound in a multilamellar sheath that is formed by a high lipid content and proteins. The myelin sheath is related to motor, sensory, and cognitive development and is the most recent evolution of the nervous system among the human species (Van der Knaap et al., 1991).
Sciencedirect.comMyelin Sheath: What It Is, Purpose & Function - Cleveland Clinic
WEBMay 9, 2022 · Myelin Sheath. The myelin sheath is a protective membrane that wraps around part of certain nerve cells. Myelin also affects how fast signals travel through those nerve cells. Several diseases and conditions — multiple sclerosis being the most well-known — damage or destroy myelin.
My.clevelandclinic.orgMyelin - Wikipedia
WEBThe process of generating myelin is called myelination or myelinogenesis. In the CNS, oligodendrocyte progenitor cells (OPCs) differentiate into mature oligodendrocytes, which form myelin. In humans, myelination begins early in the 3rd trimester, [11] although only little myelin is present in either the CNS or the PNS at the time of birth
En.wikipedia.orgMyelination of the Nervous System: Mechanisms and Functions
WEBIn this review, we highlight recent advances in our understanding of myelin biogenesis, its lifelong plasticity, and the reciprocal interactions of myelinating glia with the axons they ensheath. In the central nervous system, myelination is also stimulated by axonal activity and astrocytes, whereas myelin clearance involves microglia/macrophages.
Annualreviews.orgThe Initial Myelination in the Central Nervous System
WEBMar 27, 2023 · In this review, we first summarize the key processes of initial myelination. Next, we highlight current progress in our understanding of mechanisms of initial CNS myelination from the aspects of transcription factors, extracellular factors, axonal regulation, and signaling pathways.
Ncbi.nlm.nih.govMyelin: An Overview - BrainFacts
WEBMar 24, 2015 · Communication between neurons depends on the spread of electrical signals, and, just as wires need to be insulated, so too do neurons. Myelin was discovered in the mid-1800s, but nearly half a century passed before scientists discovered its …
Brainfacts.orgMyelination: Current Biology - Cell Press
WEBOct 24, 2016 · By promoting rapid, efficient nerve conduction, myelination also made possible the development of the large body size of these vertebrates. In addition to increasing the speed of nerve conduction, myelination has emerged as a source of plasticity in neural circuits that is crucial for proper timing and function.
Cell.comPeriods of synchronized myelin changes shape brain function and
WEBOct 28, 2021 · We discuss potential mechanisms of myelination at different life stages, explore whether myelin plasticity provides the regenerative potential of the CNS white matter, and question whether
Nature.comMyelin, Membrane | Learn Science at Scitable - Nature
WEBHow do we structure a research effort to elucidate the mechanisms involved in developmental myelination and demyelinating diseases? We need to develop useful models to test drugs or to modify
Nature.com