Isatuximab
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Isatuximab - Wikipedia
WEBisatuximab, sold under the brand name Sarclisa, is a monoclonal antibody (mAb) medication for the treatment of multiple myeloma.. The most common side effects include neutropenia (low levels of neutrophils, a type of white blood cell), infusion reactions, pneumonia (infection of the lungs), upper respiratory tract infection (such as nose and …
En.wikipedia.orgIsatuximab Uses, Side Effects & Warnings - Drugs.com
WEBApr 2, 2024 · isatuximab side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.. Some side effects may occur during the injection. Tell your caregiver if you feel cold, itchy, nauseated, feel like you might pass out, or have a cough, headache, stuffy or runny …
Drugs.comisatuximab | Cancer Care Ontario
WEBDrug Formulary information is intended for use by healthcare professionals. It is not intended to be medical advice. Some of the information, including information about funding for cancer drugs, does not apply to all patients.
Cancercareontario.caIsatuximab: A Review of Its Use in Multiple Myeloma - PMC
WEBAug 5, 2021 · isatuximab (Sarclisa ®; isatuximab-irfc in the USA) is an anti-CD38 monoclonal antibody (mAb) approved for use in the treatment of adults with multiple myeloma (MM): in combination with pomalidomide and dexamethasone for those with relapsed and refractory MM (RRMM) who have received ≥ 2 prior therapies, including …
Ncbi.nlm.nih.govIsatuximab in the Treatment of Multiple Myeloma: A Review and
WEBJul 29, 2022 · Mechanisms of Action. isatuximab is an immunoglobulin G (IgG) 1 monoclonal antibody directed against a distinct epitope on CD38. isatuximab mediates MM cell death through multiple mechanisms, including antibody-dependent cellular phagocytosis (ADCP), complement-dependent cytotoxicity (CDC), and antibody-dependent cellular …
Ncbi.nlm.nih.govIsatuximab, Bortezomib, Lenalidomide, and Dexamethasone for …
WEBJun 3, 2024 · A total of 446 patients underwent randomization. At a median follow-up of 59.7 months, the estimated progression-free survival at 60 months was 63.2% in the isatuximab-VRd group, as compared with
Nejm.orgDRUG NAME: Isatuximab - BC Cancer
WEBisatuximab has not been studied in pregnant women or study animals. Human IgG1 is known to cross the placental barrier; therefore, as an IgG1-derived antibody, isatuximab is expected to be transmitted from mother
Bccancer.bc.caIsatuximab: Uses, Interactions, Mechanism of Action - DrugBank …
WEBMay 20, 2019 · Generic Name isatuximab DrugBank Accession Number DB14811 Background. isatuximab (formerly SAR650984) is a humanized, IgG1-derived monoclonal antibody (mAb) produced from a Chinese hamster ovary (CHO) cell line. 9,2 Structurally, isatuximab is comprised of two identical immunoglobulin kappa light chains and two …
Go.drugbank.comSarclisa: Uses, Dosage, Side Effects, Warnings - Drugs.com
WEBSep 4, 2023 · Sarclisa (isatuximab) is used for the treatment of multiple myeloma. Information includes Sarclisa side effects, warnings, interactions and indications.
Drugs.comIsatuximab: A Review of Its Use in Multiple Myeloma - PubMed
WEBisatuximab (Sarclisa ®; isatuximab-irfc in the USA) is an anti-CD38 monoclonal antibody (mAb) approved for use in the treatment of adults with multiple myeloma (MM): in combination with pomalidomide and dexamethasone for those with relapsed and refractory MM (RRMM) who have received ≥ 2 prior therapies, including lenalidomide and a …
Pubmed.ncbi.nlm.nih.gov