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Endotoxin | Gram-negative, Lipopolysaccharide, Immune Response
WEBendotoxin, toxic substance bound to the bacterial cell wall and released when the bacterium ruptures or disintegrates. endotoxins consist of lipopolysaccharide and lipoprotein complexes.
Britannica.comLipopolysaccharide - Wikipedia
WEBLipopolysaccharide, now more commonly known as endotoxin, is a collective term for components of the outermost membrane of cell envelope of Gram-negative bacteria, such as E. coli and Salmonella. with a common structural architecture.
En.wikipedia.orgEndotoxin - an overview | ScienceDirect Topics
WEBendotoxins (lipopolysaccharides from the membrane of gram negative bacteria) make up the majority of pyrogens which must be removed from pharmaceutical products, biologicals for injection and some media for tissue cultures. endotoxins in solution range from molecular weights of 10,000 to 1,000,000.
Sciencedirect.comBacterial endotoxins: biological properties and mechanisms of action
WEBendotoxins (lipopolysaccharides, LPS) are agents of pathogenicity of Gram-negative bacteria, implicated in the development of Gram-negative shock. endotoxin reacts with lipopolysaccharide-sensitive cells producing endogenous mediators such as tumour necrosis factor alpha (TNFα).
Ncbi.nlm.nih.govEndotoxin - an overview | ScienceDirect Topics
WEBendotoxin is one of the most important bacterial components contributing to the inflammatory process. Levels of endotoxin correlate directly with severity of meningococcal disease and other forms of sepsis, and with elaboration and release of inflammatory mediators. endotoxin upregulates TNF-α, IL-1 and IL-6, complement and coagulation …
Sciencedirect.comBacterial endotoxins and exotoxins in intensive care medicine
WEBMar 12, 2022 · This article discusses bacterial toxins and describes the common disease states they cause. Toxins are generally categorised into endotoxins and exotoxins. endotoxins are lipopolysaccharides (LPS) and cause Gram-negative sepsis. Exotoxins are peptides that are mostly secreted by Gram-positive bacteria.
Ncbi.nlm.nih.govThe Importance of Food for Endotoxemia and an Inflammatory …
WEBSep 3, 2021 · The most important endotoxin is LPS, being a superantigen. In this narrative review, the effect of various food components to postprandially elevate circulating LPS and inflammatory markers is described.
Ncbi.nlm.nih.govEndotoxin - an overview | ScienceDirect Topics
WEBendotoxin is a phospholipid that forms the outer membrane of most Gram-negative bacteria. Circulating endotoxin binds lipopolysaccharide-binding protein, forming a complex that interacts with the MD-2 part of TLR4, anchored by the CD14 receptor [129].
Sciencedirect.comThe role of endotoxin in septic shock | Critical Care | Full Text
WEBOct 19, 2023 · Endotoxic septic shock (ESS), defined by high endotoxin activity (e.g., EAA > 0.6) and organ failure (e.g., SOFA > 7, appears to be a subtype of sepsis accounting for approximately 5–7 million cases annually worldwide.
Ccforum.biomedcentral.comEndotoxin: Structure Source and Effects | SpringerLink
WEBJan 13, 2023 · endotoxins are insoluble parts of the bacterial cells able to evoke a typical clinical picture characterizing bacterial infection. Usually, Gram-negative bacteria are a major part of the gut microbiota and are a source of endotoxins, particularly lipopolysaccharide (LPS).
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