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CLIF-C ACLF (Acute-on-Chronic Liver Failure) - MDCalc
WEBCLIF-C aclf (Acute-on-Chronic Liver Failure) Predicts mortality in acute-on-chronic liver failure. INSTRUCTIONS. Use in adult patients with decompensated chronic (cirrhotic) liver disease; it does not predict outcome in acute liver failure. When to Use. Pearls/Pitfalls. Why Use. Age. years. WBC count. × 10³ cells/µL. Liver. Bilirubin.
Mdcalc.comAcute on Chronic Liver Failure - StatPearls - NCBI Bookshelf
WEBApr 13, 2023 · Acute on chronic liver failure (aclf) is a clinical syndrome of sudden hepatic decompensation observed in patients with pre-existing chronic liver disease and associated with one or more extrahepatic organ failures and increased mortality.[1][2][3][4]
Ncbi.nlm.nih.govAcute-on-chronic liver failure (ACLF) - EMCrit Project
WEBFeb 14, 2021 · aclf refers to the most severe subset of patients with acutely decompensated cirrhosis, who are at higher risk of short-term mortality. There is disagreement about the precise definition of aclf.
Emcrit.orgAcute-on-chronic liver failure: Definitions, pathophysiology and
WEBSep 2, 2020 · The term acute-on-chronic liver failure (aclf) defines an abrupt and life-threatening worsening of clinical conditions in patients with cirrhosis or chronic liver disease. In recent years, different definitions and diagnostic criteria for the syndrome have been proposed by the major international scientific societies.
Ncbi.nlm.nih.govEASL Clinical Practice Guidelines on acute-on-chronic liver failure
WEBJun 24, 2023 · Acute-on-chronic liver failure (aclf), which was described relatively recently (2013), is a severe form of acutely decompensated cirrhosis characterised by the existence of organ system failure (s) and a high risk of short-term mortality.
Journal-of-hepatology.euAcute-on-chronic Liver Failure and the Management - AASLD
WEBThis document from the American Association for the Study of Liver Diseases (AASLD) serves to provide guidance and a data-supported approach for the diagnosis, evaluation, and management of patients with cirrhosis and aclf as well as cirrhosis and critical illness.
Aasld.orgAcute-on-Chronic Liver Failure | New England Journal of Medicine
WEBMay 27, 2020 · The course of aclf was extremely dynamic — resolving, improving, or worsening, frequently within a few days, in a substantial number of patients or changing after a steady course.
Nejm.orgAcute-on-chronic liver failure - PMC - National Center for
WEBAcute-on-chronic liver failure (aclf) is a recently recognised and defined syndrome seen in patients with liver cirrhosis and carries a high short-term mortality in excess of 15% at 28 days. aclf is defined by organ failures (OFs) and is distinct from simple ‘acute decompensation’ (AD) of cirrhosis.
Ncbi.nlm.nih.govIBCC – Acute on Chronic Liver Failure (ACLF) - EMCrit Project
WEBMar 15, 2021 · Acute on Chronic Liver Failure (aclf) refers to decompensated cirrhosis causing failure of at least two organs (e.g. hepatic encephalopathy, hepatorenal syndrome, shock, or respiratory failure).
Emcrit.orgAcute-on-Chronic Liver Failure - MDCalc
WEBIn hospitalized decompensated cirrhotic patients, we recommend assessment for infection because infection is associated with the development of aclf and increased mortality.
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